As many have been speculating for the last year or so, the Full Metal Alchemist manga is now nearing its end, with Arakawa Hiromu formally announcing that the last chapter of the manga will be published in the July issue of Monthly Shounen Gangan. This leaves only two chapters before the end of the series.
The anime based on the manga, Full Metal Alchemist: Brotherhood, is going to run such that it's ending will air simultaneously to the publishing of the final chapter of the manga, as was planned from the beginning it would seem.
Personally, I think there's a lot of ground to cover in regard to the resolution of the plot with only two chapters remaining, as it seems the final fight against Homunculous is reaching its own climax in the next chapter...this would leave only one chapter remaining after the fight. Not quite sure how Arakawa will go about handling this.