Well let's see. People swap gender, dress up in clothes of other gender with no discernable way to tell the difference, have sex changes, and sometimes have two people of different gender in the same body. Not to mention the yaoi and yuri. And booze.
Discuss. Does it matter? Creep you out? Should true love conquer all even if the one you are attracted to might have a surprise for you? Who can you name who fits this category?